1. Constipation
2. Relief of the following symptoms accompanying constipation:
- heavy head feeling
- hot flash
- eczema / dermatitis
- pimples
- poor appetite
- abdominal bloating
- abnormal intestinal fermentation
- hemorrhoids

Take the following dose with water or warm water without chewing.
Mild constipation (no bowel movement for 2 - 3 days)
Adults (15 years and over): 1 to 3 tablets once a day, before bedtime
Children (5 - 14 years): 0.5 to 1.5 tablets once a day, before bedtime
Severe constipation (no bowel movement for 4 days or longer)
Adults (15 years and over): 2 to 4 tablets once a day, before bedtime
Children (5 - 14 years): 1 to 2 tablets once a day, before bedtime
Start medication with the minimum dose, and adjust it according to your bowel movements.

Maximum daily dose (4 tablets) contains 400 mg of a dried extract of the following mixed crude drugs.
Rhubarb ･･････････････････････････････ 1,600 mg
Licorice ･･････････････････････････････ 400 mg
Additives: cellulose, maltose syrup powder, magnesium aluminometasilicate and magnesium stearate.

1. This product is a relatively mild laxative which stimulates the colon to promote intestinal peristalsis.
2. It mainly consists of "Daiokanzoto Extract" (Kampo formula with rhubarb and licorice), which has been widely used for treatment of constipation since long time ago.
3. It is recommended for first-time laxative users, those who have relatively mild constipation and elderly people with weak digestion.
4. Since the active component "sennoside A" is activated by intestinal bacteria, concomitant use of medicines which reduce intestinal bacteria (e.g. antibiotics) should be avoided.
5. Constipation is often caused by weakened intestinal peristalsis due to stress or fatigue. It is recommended to take the medicine together with vitamin B1 to increase peristalsis.

1. Do not take any other laxatives (cathartics) while taking this medicine.
2. Do not take this medicine while breastfeeding, or stop breastfeeding during medication.
3. Do not take in large doses.
4. Consult your doctor or pharmacist before starting medication, if:
(1) you are under medical treatment,
(2) you are pregnant or possibly pregnant,
(3) you are physically weak,
(4) you have poor digestion and often get diarrhea,
(5) you have experienced allergic reactions to any medicine, or
(6) you are having severe abdominal pain, nausea or vomiting
5. If the following symptoms occur after taking this medicine, discontinue the medication immediately and consult your doctor or pharmacist showing the package insert.
- rash, reddening, itch
- diarrhea with severe abdominal pain, abdominal pain, nausea, vomiting
6. The medicine may cause diarrhea. If it persists or worsens, discontinue the medication and consult your doctor or pharmacist showing the package insert.
7. If no improvement is seen after 5 to 6 days of medication, discontinue the medication and consult your doctor or pharmacist showing the package insert.