To promote hair growth in premature alopecia and prevent the progression of hair loss (fallen hair)

For an adult woman (≧ 20 years old), apply 1 mL on the scalp with hair loss twice a day.
Use 1 mL per dose regardless of the size of the affected area. A dose of 1 mL is sufficient for spreading the drug on the entire scalp.
The container is designed to measure 1 mL.
A dose exceeding the range designated by the dosage and administration instructions or a more frequent application does not affect the efficacy. Strictly comply with the specified dosage and administration.
(If you use the drug with more than the prescribed dose, the effect hardly increases, and adverse reactions are more likely to occur.)
If you have long hair, push aside the hair to reveal the scalp. Prevent the drug solution from staining the hair, and carefully apply the drug on the scalp.
If you touch a mucous membrane (e.g., the eyes) with fingers stained with the drug solution, irritation will occur. Wash your hands well to remove the drug solution.
Attention should be paid so that the medicine will not come into contact with eyes. If the medicine comes into contact with eyes, immediately rinse them with water or lukewarm water. If the symptoms are severe, seek an ophthalmologist for medical treatment.
Do not stain objects that might melt with alcohol (glass frames, chemical fiber, etc.) with the drug.
Use hair styling agents and hair spray after applying the drug.
If you use hair dye (hair color, gray hair dye, etc.), apply the drug after the hair dye is completely finished.
If you wear a wig or hairpiece, you should wear it after the drug is completely dried.

In 100 mL
Minoxidil 　1.0g　
Pantothenyl ethylether　1.0g　
Tocopherol Acetate　0.08g　
l-Menthol　0.3g
Excipients
1,3-Butylene glycol,citric acid,Anhydrous ethanol,Sodium hyaluronate

Precautions
When not to use the product
(If you do not follow these instructions, the current symptoms may worsen or adverse reactions/incidents are more likely to occur.)
This product should not be used in the following persons:
Patients who have had an allergic symptom to this drug or its ingredients.
Minors (under 20 years old)
The product has not been used in Japan.
Pregnant women or women suspected of being pregnant, as well as nursing women
Safety in the use during pregnancy has not been sufficiently confirmed. Minoxidil is excreted in mother's milk.
Hair loss associated with pregnancy or child birth
They are highly likely to be alopecia other than premature alopecia.
Hair loss due to the cessation of use of contraceptive pills
Alopecia other than premature alopecia (e.g., thyroid disease, crash diet, and alopecia areata) or alopecia with an unknown cause.
The drug is effective only for premature alopecia.
Hair loss of the entire scalp (not only at the top but also the sides and back).
Alopecia may be caused by any factor other than premature alopecia, such as hair loss due to thyroid disease, which occurs more in women than men. Hair loss may also be caused by other factors.
Acute hair loss and spotty hair loss
They are highly likely to be alopecia other than premature alopecia.
Hair loss due to the hair style that pulls hair strongly from the scalp.
They are highly likely to be alopecia other than premature alopecia.
Men
Male patients should use RiUP series for men.
Do not use in the following sites.
Use the drug only for the scalp. Do not take it orally.
Blood pressure may decrease.
Scalp with wound, eczema or inflammation (redness), etc.
The drug may worsen the wound.
When you use this drug, do not use other hair growth agents and external preparations (ointment, liquid drug, etc.) in the scalp. When you use these other drugs, stop using this drug.
These other drugs may affect the absorption of this drug.
Consultation
The following persons should contact a physician or pharmacist for a consultation before using the drug:
Persons who have experienced allergic symptoms (e.g., rash/redness, itching, and eruption) associated with drugs and cosmetics.
Persons with hypertension/ hypotension
The drug may possibly affect blood pressure.
Persons with heart or kidney disorder
The drug may affect the heart and kidneys.
Persons with oedema
The drug may worsen oedema.
Persons whose family and siblings have no premature alopecia.
It is considered that genetic factors affect hugely the onset of premature alopecia.
The elderly (≧65 years old)
Generally, unfavorable symptoms are likely to occur in the elderly.
Persons with the following diagnoses:
Thyroid disease (hypothyroidism and hyperthyroidism)
The hair loss may be caused by thyroid disease.
If the following symptoms are observed after taking this drug, these may be adverse reactions, so immediately discontinue the use of this drug, and show this document to a physician or pharmacist for a consultation
Skin: rash/redness in scalp*, itching, eruption, dandruff, feeling hot in the application site, etc.
Neuropsychiatric system: headache, faint, and dizziness
Cardiovascular system: chest pain and increasing heart rate
Metabolic system: sharp increase of body weight with unknown cause and oedema in the extremities
*: The symptoms may occur in sites other than the scalp.
If none of the following improvements are achieved after using the drug for 6 months, stop using this medicine, and show this document to a physician or pharmacist for a consultation.
Alopecia may be caused by any factor other than premature alopecia, such as hair loss due to thyroid disease, which occurs more in women than men. Hair loss may also be caused by other factors.
Severity of hair loss, hair growth/soft hair growth, terminal hair growth, and amount of fallen hair (the decrease of not only bold fallen hair but also thin fallen hair is...
Precautions for storage and handling
After using the product, put the cap, avoid direct sunlight and high and extremely low temperatures, and store it in a cool place.
Store the product beyond the reach of children.
Do not transfer the drug to other containers to prevent misuse and quality deterioration.
Do not place the drug close to any source of flame.
Do not take the product past the expiration date.